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https://www.selleckchem.com/products/ABT-888.html
BACKGROUND AND PURPOSE Protective mechanisms of the endogenous cannabinoid (eC system against drug-induced liver injury (DILI) are actively being investigated regarding the differential regulatory role of the cannabinoid CB1 and CB2 receptors in liver fibrogenesis and inflammation. EXPERIMENTAL APPROACH The 2-arachidonoyl glycerol (2-AG)-related signaling receptors and enzymatic machinery, and inflammatory/fibrogenic factors were investigated in the liver of a mouse model of hepatotoxicity induced by acute and repeated overdoses (750

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