https://www.selleckchem.com/pr....oducts/nedisertib.ht
Almost 50% of the patients with hyponatremia and all four patients in whom all four predictors were present together discontinued the trial early. Hyponatremia, elevated alkaline phosphatase level, performance score ≥ 1 and opioid use were identified as significant predictors for early trial discontinuation. Hyponatremia was the strongest predictor and deserves consideration for inclusion in eligibility criteria for future trials.The blue blood of the horseshoe crab is a natural, irreplaceable, and precious resource that is highly va
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