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INTRODUCTION. Epidemiological, clinical, and treatment response characteristics of major depression with anxious distress (ADS) are quite similar to those of mixed depression, but no study investigated the symptom interplay of these conditions. OBJECTIVE. To analyze the correlations among symptom criteria for major depression with ADS and for mixed depression using a network analysis. METHODS. Two hundred and forty-one outpatients with major depression were consecutively recruited. DSM-5 criteria for major depression with ADS or with mi
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