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Copy number variations (CNVs) account for a substantial proportion of inter-individual genomic variation. However, a majority of genomic variation studies have focused on single-nucleotide variations (SNVs), with limited genome-wide analysis of CNVs in large cohorts, especially in populations that are under-represented in genetic studies including people of African descent. We carried out a genome-wide copy number analysis in 3400 healthy Bantu Africans from Tanzania. Signal intensity data from high density ( 2.5 million probes