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Further research is needed. To assess the feasibility of real-time monitoring of work of breathing (WO indices and the impact of adjusting HFNC flow on breathing synchrony and oxygen stability in premature infants. A prospective, observational study of infants stable on HFNC. The flow adjusted per predetermined algorithm. Respiratory inductive plethysmography (RIP) noninvasively measured WOB. A high-resolution pulse oximeter collected oxygen saturation and heart rate data. Summary statistics and mixed linear models were used. Baseline d

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