https://www.selleckchem.com/pr....oducts/chir-99021-ct
White matter tract integrity was assessed in all segments and compared with MRI data acquired from 25 healthy controls. Results In the combined patient group, the most prominent differences in diffusivity metrics were in the rostral body, posterior midbody and isthmus of the corpus callosum (p less then 0.04). Loss of corpus callosum integrity was most prominent in the sub-group with unilateral limb weakness at the time of scanning (p less then 0.05). Conclusions Corpus callosum involvement in ALS is detectable across
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