https://www.selleckchem.com/pr....oducts/CHR-2797(Tose
Germline mutations in GATA2 are associated with an inherited predisposition to bone marrow failure (BMF), myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Hematopoietic stem cell transplantation (HSCT) remains the only curative therapy. However, patients may be at an increased risk for transplant-related toxicity (TRT) and mortality (TRM) due to their underlying disease biology. We performed a retrospective case-control study of pediatric BMF/MDS/AML patients with germline GATA2 mutations, comparing HSCT ou
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