https://www.selleckchem.com/pr....oducts/arry-380-ont-
This, however, was different in LS174T cells, which showed no significant increase in gene expression although the methylation levels were significantly decreased at a variety of corresponding loci. We suggest that the mechanism induced by methylation on gene expression in metastatic CRC cells can be compromised. The results question the overall success of treating metastatic CRC by methylation inhibitors. Copyright © 2020 Mahdi, Georges, Ali, Bedeer, Eltahry, Gabr and Berger.Pharmacometric methods have hugely benefited from pr