https://www.selleckchem.com/pr....oducts/tbk1-IKKe-in-
Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the brain at least 99% of all cerebellar neurons are granule cells. In this review article, we first consider the formation of the upper rhombic lip, from which all granule cell precursors arise, and the way by which the upper rhombic lip generates the external granular layer, a secondary germinal epithelium that serves to amplify the upper rhombic lip precursors. Next, we review the mechanisms by which postmitotic granule cells are gen
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