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Differential regulation of MMP1 was confirmed with RT-qPCR and ELISA. Additionally, RL upregulated PRSS35, which has not been previously associated with skin activity, but has known anti-fibrotic functions. Our results suggest that RL may benefit patients by altering fibrotic gene expression.Optical prisms are made of glass and map temporal frequencies into spatial frequencies by decomposing incident white light into its constituent colors and refract them into different directions. Conventional prisms suffer from their volumetric bulky and heavy structure