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To assess the risk of VT, odds ratios (ORs) were calculated after stratification of coagulation factors in quartiles and at the 90th percentile, adjusting for potential confounders (age, sex, body mass index, and study center). Results Mean age was 78 years (range 70-100 years). The ORs of VT for factors in the top quartile compared with the lowest quartile were 4.5 (95% confidence interval [CI]2.7-7.3) for factor VIII, 2.4 (95% CI1.1-5.2) for factor IX, and 1.7 (95% CI1.0-2.9) for factor XI. High prothrombin was not associated with an