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There are no criteria to estimate the risk of early discharge after anatomic lung resection (ALR). We hypothesized that demographic, clinical, and surgical variables could be used to predict successful post-operative day 1 (POD1) discharge after ALR. Patients with POD1 discharge after ALR were identified in the STS database from 2012-2018. Discharges were categorized as "successful" based on freedom from complications, readmission, or death. A multivariable model identified variables from univariate analysis and was further optimized u