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In 242 ESRD patients (median age 55years, 61% guys) beginning dialysis with peritoneal dialysis (PD; n = 138) or hemodialysis (HD; n = 104), whole-body dual-energy X-ray absorptiometry (DXA), body structure, nutritional standing and circulating biomarkers were evaluated at standard and 1year after dialysis begin. We used multivariate linear regression analysis to ascertain factors associated with ΔBMD, and good and gray contending threat analysis to find out organizations of ΔBMD with subs