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College freshmen are at high risk for mental and socioemotional problems after entering a new environment. However, few investigators have evaluated the associations between empathy and depressive symptoms among college freshmen. The present study examined the presence and associations of affective and cognitive empathy with depressive symptoms among college freshmen in China. In total, 4297 college freshmen completed the Interpersonal Reactivity Index as an assessment of empathy and the University Personality Inventory to evaluate the