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These findings suggest that distinct Rho GTPases may act as context-dependent integrators of chemotactic cues in directional cell migration and may serve as candidate therapeutic targets to manipulate cell motility in disease or tissue regeneration. © 2020 The Authors.Child undernutrition remains a considerable problem in poor regions, due to unhygienic living conditions and chronically infected guts that make it hard to absorb nutrients. Undernutrition may negatively affect child development (1) and findings suggest that impaired gut microbiota may