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sential for the understanding and valuation with regard to future optimal management of patients with HF. Our data showed a significant reduction of urgent hospital admissions for HF with increased case severity and concomitant in-hospital mortality during the COVID-19 pandemic in Germany. Identifying causes of reduced inpatient treatment rates is essential for the understanding and valuation with regard to future optimal management of patients with HF.Free-air CO2 enrichment (FACE) allows open-air elevation of [CO2 ] without altering th