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magna exposed to unfiltered piggery effluent was 23.2 (17.7-30.4)%. The 24-h EC50 protozoan toxicity to T. thermophila exposed to 1% HLD veterinary pharmaceuticals was 0.014 μg/L. Thus, the study established the different sensitivities of freshwater organisms to various percentage levels of piggery effluent and high- and low-level doses of veterinary pharmaceutical. The piggery effluent and the pharmaceutical cocktail mixtures have potential toxicological effects on the freshwater ecosystem.The addition of 'clinically significant impairment' (American Psych