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The limit of detections for dopamine, uric acid and ascorbic acid are 1.3 × 10-8, 2.6 × 10-8 and 3.7 × 10-8 M, respectively, at least one order lower than that achieved on electrochemical sensors reported previously. This work provides a versatile method for efficient preparation and stabilization of monodisperse metallic NPs in diverse porous materials, leading to possible applications in devices, catalysis, and electrochemical sensing. Due to its toxicity and persistence, pesticide pollution poses a serious threat to human health an