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Challenges of ADHD in Women and Girls Untreated ADHD symptoms can cause various issues for girls and women. They may feel inadequate at work, have difficulty with peer relationships and suffer from anxiety or depression. They also tend to be better in establishing coping mechanisms that mask their ADHD symptoms, which makes it difficult for them to be diagnosed and treated. Symptoms Although research has proven that ADHD affects men and boys at a higher rate than women and girls however, the gap between the genders shrinks as people age. This is why it's vital th