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In this work, existing understanding on expression and regulation of CYP4B1 gene and protein, catalysis of CYP4B1, relationship of CYP4B1 with cancers, contradicting conclusions about human CYP4B1 tasks plus the using CYP4B1 in suicide gene method for disease treatment were evaluated. Up to now, it would appear that there clearly was an extensive spectrum of muscle distribution of CYP4B1 with lungs since the predominant sit