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Furthermore, we created a novel prognostic nomogram centered on threat score and 3 clinicopathological aspects. Our study indicated possible methylation-related DEGs and established an epigenetic trademark, which could supply novel ideas for comprehending the pathogenesis of esophageal cancer.Our study suggested possible methylation-related DEGs and established an epigenetic signature, that might provide unique insights for knowing the pathogenesis of esophageal cancer.Green tea, and its