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Excess plant tissue element concentrations and element concentrations in soil solutions were reduced in amended soils. The implications are that adding WTRs to mining impacted soils is a potentially viable, sustainable and low cost remediation method that could be used globally to improve the soil condition. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.Heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (BDNF) in the prefronta