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This review aims to compare different available tendon in vitro differentiation strategies to clarify the state of art regarding the differentiation process.We use a spectral approach to model residually stressed elastic solids that can be applied to carbon fiber reinforced solids with a preferred direction; since the spectral formulation is more general than the classical-invariant formulation, it facilitates the search for an adequate constitutive equation for these solids. The constitutive equation is governed by spectral invariants