https://idotdosignal.com/index.....php/looking-at-impo
Herein, an on-tissue chemical derivatization method predicated on absolutely recharged hydrazine reagent (Girard's reagent P) along with matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) was created for evaluation of N-glycans from FFPE treated tissue sections. The overall performance for the proposed method was evaluated by analysis of monosaccharides, oligosaccharides, N-glycans introduced from glycoproteins, in addition to MS imaging of N-g
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