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How to Choose the Best ADHD Medication for Adults Stimulant medicines like methylphenidate or amphetamine are effective in boosting and balancing brain chemicals. Doctors prescribe them as pills, liquids or patches. ADHD can be treated by health professionals using drugs known as alpha-2 agonists and norepinephrine-reuptake inhibitors. They're usually prescribed "off-label" to treat this condition because they're FDA-approved for use to treat other conditions. Stimulants The stimulants are among the most common ADHD medication prescribed.