https://v-9302antagonist.com/c....d73-term-specifies-i
We previously demonstrated that after administering adeno-associated viral (AAV) vector-mediated genome-editing strategies in vivo, vector sequences incorporated into the host organism's genomic DNA at double-stranded pauses. Thus, distinguishing the genomic area of inserted AAV sequences would allow us to spot DSB occasions, primarily produced by the nuclease on- and off-target task. OUTCOMES Here, we developed a next-generation sequencing assay that