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Finding the Best ADHD Medication For Adults Many adult ADHD treatment programs are based around medication. But finding the right medication and dosage isn't always simple. Stimulants: These drugs can be used to treat both hyperactivity as well as inattention. They work by increasing the levels of brain chemicals that pass messages between nerve cells. They are administered several times per day and begin working in under an hour. Stimulants The majority of doctors begin with stimulants to