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ADHD Medications - What Are the Side Effects? Many people with ADHD are medicated. It can ease symptoms, but it can also have negative effects. Talk to your doctor if you experience side effects. Stimulants are the most commonly prescribed kind of prescription medication that healthcare providers prescribe for ADHD. These medicines increase levels of brain chemicals known as neurotransmitters, which regulate attention and behavior. Methylphenidate Methylphenidate is a stimulant of first choice used to treat ADHD in children an