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No thrombotic complications were reported under DOAC until last follow-up (14.1 ± 13 months). In comparison to 50 controls under VKA during the same period, the bleeding rate under DOAC was significantly lower (11.5 versus 22.9 per 100 patient-years, p=0.037) with a Hazard Ratio of 0.39 (95% CI, 0.19-0.85, p=0.041). No significant changes in kidney function, rejection rate or hemoglobin level were reported. CONCLUSIONS DOACs appear to be effective and safe anticoagulants in kidney transplant recipients with stable renal function.BACKGROUN