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22, 95% CI 0.70-2.13, p = .479) and pigmentation (OR = 0.48, 95% CI 0.18-1.31, p = .153), but CAE had a lower risk of ecchymosis (OR = 0.45, 95% CI 0.25-0.81, p = .007) and paresthesia (OR = 0.16, 95% CI 0.03-0.99, p = .049). Cyanoacrylate embolization and RFA demonstrated no significant differences in VCSS, AVVQ, closure rate, and pain score for patients with incompetent GSVs. Patients in the CAE group had a lower risk of ecchymosis and paresthesia compared with the RFA group. Cyanoacrylate embolization and RFA demonstrated no signif