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The endoscopic retrograde cholangiopancreatography (ERCP) procedure is generally performed in patients with high comorbidity. We aimed to reduce the consumption of propofol by adding lidocaine before ERCP. Eighty ERCP patients with ASA I-III, aged between 45-75years, were randomly divided into two groups. Lidocaine group (group L, n=4, received 1-mg midazolam, 1.5mg/kg lidocaine, and 1mg/kg propofol intravenously. The control group (group C, n=4 received 1-mg midazolam, saline in the same volume as the lidocaine group, and 1mg/kg prop