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00001, MD = 0.17, 95% CI 0.13-0.2, segmental lesion (p 0.00001, MD = 0.15, 95% CI 0.03-0.26), tubulointerstitial damage (p 0.00001, MD = 1.27, 95% CI 1.06-1.48), and glomerulosclerosis (p 0.00001, MD = 0.56, 95% CI 0.40-0.72) were considerably climbed in IgAN patients with hyperuricemia compared without hyperuricemia group. Additionally, the estimated glomerular filtration rate (p 0.00001, MD = - 29.03, 95% CI - 36.83 to - 21.23) was decreased in IgAN patients with hyperuricemia compared with normouricemic group. Hy