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We performed a systematic literary works search regarding the PubMed, Cochrane and Embase databases to be able to recognize clinical studies and case-series reporting from the security and efficacy of intraperitoneal chemotherapy in patients with PDAC-derived PM. Eight magazines stating on 85 patients were identified, utilizing three different therapeutic methods. First, 37 patients got cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) for PDAC with PM. Grade