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ADHD Medications For Adults and Teenagers When a person's ADHD medication starts to work correctly, they will be able to focus for longer periods of time. They might also fall asleep more easily. Stimulants are among the most commonly used medications prescribed for ADHD in adults. They can be immediate-release or long-acting. Long-acting formulations prevent "crash" effects that occur after the stimulant medication has worn off. Methylphenidate Methylphenidate stimulates the