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R 3.6.2 pc software had been used for statistical evaluation. Results Twelve studies concerning 10,896 customers had been included for analyses. The outcomes revealed that the high-dose group had better OS (HR = 0.79, 95% CI = 0.70-0.90, P = 0.0004) in addition to local-regional control (OR = 0.59, 95% CI = 0.46-0.76, P 50.4 Gy revealed no significant difference between OS (HR = 0.98, 95% CI = 0.93-1.03, P = 0.43). In addition, there are not any considerable differences