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05), but not forced expiratory volume in 1s (FEV ), FEV /FVC, 6MWD, or quality of life (all p0.05). The annual negative PMA slope was associated with annual negative slopes in FVC, FEV , and DL (all p0.05), but not FEV /FVC (p=0.46). Annual slope in PMA was associated with all-cause mortality (hazard ratio=-0.80, 95% CI0.889-0.959; p0.001). In patients with ILD, PMA is a suitable surrogate for whole-body lean mass. A lower PMA is associated with indices of ILD severity, which supports the notion that ILD p