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MChSA micelles, which can target TDLN to induce potent antitumor immune responses as antigen-capturing adjuvants, exhibit great potential in individualized disease immunotherapy.Poloxamer 407 (polox407) is commonly examined as thermogelling polymer, transitioning to a gel state when warmed Polox407 types weak hydrogels with quick dissolution in extra solvent. This research reports the development of binary systems composed of polox407 and hydroxypropyl methylcellulose (HPMC) or sodium carboxymethylcellu