https://www.selleckchem.com/pr....oducts/derazantinib.
Consensus for defining gross tumor volume (GTV) and clinical target volume (CTV) for limited-field radiation therapy (LFRT) of GBM are not well established. We leveraged a department MRI simulator to image patients before and during LFRT to address these questions. Supratentorial GBM patients receiving LFRT (46Gy+boost to 60Gy) underwent baseline MRI (MRI1) and interim MRI during RT (MRI2). GTV1 was defined as T1 enhancement+surgical cavity on MRI1 without routine inclusion of T2 abnormality (unless tumor did not enhance). The init
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