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© RSNA, 2020.Background Diffusion-weighted imaging (DWI) can depict the swollen synovial membrane layer in arthritis. Purpose To learn the diagnostic accuracy of DWI when it comes to detection of joint disease compared with the clinical reference standard and to compare DWI to contrast material-enhanced MRI when it comes to recognition of synovial irritation. Materials and techniques In this institutional review board-approved potential research, 45 part