https://www.selleckchem.com/pr....oducts/nec-1s-7-cl-o
Desmopressin orally disintegrating tablet (ODT) was approved in March 2012 in Japan; the post-market safety reports, which warned about adequate initial dose of desmopressin ODT, were published in 2014. However, it is unclear how the warning affected physician and patient behavior. We performed a retrospective single-center study to compare the clinical situation of Japanese central diabetes insipidus patients before and after the report. Thirty-four patients before October 2014 and 16 patients after November 2014 switched fr