https://rgx-104agonist.com/exa....ctly-how-should-we-m
In this work, a new UPLC-MS/MS strategy was developed and validated when it comes to multiple determination of TAM, its active metabolite 4-hydroxy tamoxifen (TOH), and DSV in rat plasma. The strategy had been applied to investigate the PK connection between DSV and TAM/TOH following co-administration of DSV and TAM to Wistar rats. Chromatographic analysis was done on Waters BEHTM C18 column using a mobile stage of acetonitrile/water containing 0.1% formic acid (80 20, v/v). The