https://www.selleckchem.com/pr....oducts/Ml-133-hcl.ht
Patients with low IGJ had a 7.2-fold (p0.001) increase in risk of disease-specific death with a median DSS of 13 months. Low IGJ showed an area under curve (AUC) of 0.89 with 91.0% sensitivity and 87.6% specificity to identify early disease-specific mortality (defined as DSS ≤12 months). Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed a global dampening of immune pathways in low IGJ tumors. Our work showed that IGJ is a robust and independent prognostic biomarker for disease-specific mortality in HPV+ HNS
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