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Adult ADHD and Comorbid Disorders Many people with ADHD suffer from comorbid disorders, like major depression (Kessler and co., 2006). Many depressed patients do not respond well to medication and could benefit from therapy. Neurotransmitters are brain chemicals that regulate and boost levels of certain brain chemicals. Stimulants such as methylphenidate and amphetamine are often prescribed. Medications Adults are able to take many different medications that are used for ADHD