https://www.selleckchem.com/pr....oducts/lotiglipron.h
414, 95% confidence interval [CI] 1.012 to 5.816, p0.001), which was attenuated when leptin was included in the model, thus indicating that leptin mediates this relationship (β =1.074, 95% CI 0.349 to 2.686, p0.001). The percentage of the total effect mediated by leptin was 21%. Regarding sex, the mediation effect of leptin remains significant among boys (β =0.962, 95% CI 0.009 to 2.615, p0.001), but not in girls (β =0.991, 95% CI 1.263 to 5.483, p=0.477). The findings are clinically relevant to consider leptin levels as
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