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The mean tumor volume was(5.1±6.7) cm³, T4 stage patients had higher tumor volume than those of patients with T3 stage(P3 cm³(P less then 0.001). Upon multivariate analyses, tumor volume was strongly correlated with poorer OS and DFS rates and remained independent prognostic factors for both the OS and DFS of patients with glottic carcinoma(OS HR=1.59, 95%CI 1.09-2.32, P=0.017; DFS HR=1.54, 95%CI 1.08-2.20, P=0.016). ConclusionThis study demonstrates that tumor volume is correlated with T stages, and this factor is an independent predic