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05, = 0.01) and the per-protocol intervention group ( 0.0001, 0.0001). For the intervention per-protocol group, the odds ratio of achieving 5% weight loss, compared to not treated per-protocol, was 3.3 (95% CI 1.3-8.2), adjusting for age and weight at baseline.Attendance to weekly coaching sessions decreased by 18% during the program in the control group while it increased by 3% amongst the per-protocol group ( = 0.004). These preliminary findings support the benefit of a digital therapeutic to enhance weight reduction and