https://www.selleckchem.com/pr....oducts/pifithrin-alp
Cytokine analyses showed signs of monocyte and macrophage activation at this stage. Fourteendays after inclusion, cytokines indicated systemic immune response as well as profiles associated to neovascularization and regeneration. Exploratory neuromuscular ultrasound and cytokine analyses showed signs of inflammation like macrophage and monocyte activation at the peak of CIPNM followed by a systemic immune response parallel to axonal damage. This underlines the role of both axonal damage and inflammation in pathogenesis of CIPNM.
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