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Among the 380,404 members, 2,733 individuals had been recently identified as having PD during a median follow-up amount of 5 years. The lowest quartile (Q1) group of baseline HDL-C and mean HDL-C was associated with increased PD occurrence when compared with all the greatest quartile (Q4) team (modified risk ratio [aHR], 1.20; 95% confidence period [CI], 1.08-1.34; and aHR, 1.16; 95% CI, 1.04-1.30, correspondingly). The Q4 selection of HDL-C variability (VIM) was related to increased PD