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get community are likely needed to maximize program benefits in terms of reduced burden of chlamydia in the adolescent population. Dexmedetomidine has advantages during colonoscopy as it allows the patient to cooperate during the procedure. Few studies examined the dexmedetomidine-remifentanil combination. was to evaluate the effects of different doses of the dexmedetomidine-remifentanil combination in colonoscopy. This was a prospective trial carried out at the Fourth Hospital of Hebei Medical University between 02/2018 and 10/2018. Th