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Most importantly, Δpbp4 S. aureus failed to invade and colonize the OLCN despite high bacterial loads on the implant and in adjacent tissues. Together, these results demonstrate that PBP4 is required for S. aureus colonization of the OLCN and suggest that inhibitors may be synergistic with standard of care antibiotics ineffective against bacteria within the OLCN. To investigate factors associated with poor visual acuity (VA) in branch retinal artery occlusion (BRAO). This was a retrospective cross-sectional study of 72 eyes with BRAO of